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Table 1 MeanSD, n = 6) flunixin meglumine plasma concentrations (ng ml-1) after a single intravenous (IV), intramuscular (IM) or oral (PO) administration in gilts

From: Pharmacokinetics of flunixin meglumine in mature swine after intravenous, intramuscular and oral administration

Administration route

Time (hours)

IV

±SD

IM

±SD

PO

±SD

0.05

21695.1

4036.6

-

-

-

-

0.10

18615.7

3638.1

-

-

-

-

0.17

22819.35

17414.12

2830.6

1237.3

-

-

0.25

-

-

-

-

537.4

231.4

0.33

10018.9

1896.4

3100.0

1224.0

-

-

0.5

8989.7

3304.1

-

-

987.8

432.9

0.67

-

-

3258.6

1565.2

-

-

1.0

3358.1

829.9

2761.1

850.1

786.2

385.1

2.0

2005.4

663.1

2264.1

380.4

869.7

337.2

4.0

908.9

254.5

1194.8

574.3

440.2

204.1

8.0

407.1

87.6

593.2

327.0

173.7

114.7

12.0

-

-

-

-

76.2

61.4

16.0

93.8

57.4

176.1

87.2

46.7

38.8

24.0

32.8

20.4

66.2

30.2

16.7

16.5

36.0

10.8

7.28

28.4

17.2

6.15

4.08

48.0

2.68

1.80

10.2

8.8

2.2

1.1

  1. Time (hours) began once drug was administered.