Figure 2

Prion protein amino acid alignment of bighorn sheep, domestic sheep (A¹³⁶R¹⁵⁴Q¹⁷¹), white-tailed deer, wapiti, mink, laboratory mouse and hamster. Green letters indicate key amino acids for scrapie susceptibility. Red letters indicate mismatches. Below sequence the alignment, consensus symbols (* identical amino acids, amino acids with strongly similar properties, amino acids with weakly similar properties) are displayed.