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Table 1 MeanSD) skin temperatures in 11 horses at the withers or nostrils

From: Nociceptive thermal threshold testing in horses – effect of neuroleptic sedation and neuroleptanalgesia at different stimulation sites

Medication Saline solution Acepromazine (0.05 mg/kg) Acepromazine (0.05 mg/kg)/Buprenorphine (0.0075 mg/kg)
Location/ Time (min) Nostril (°C) Withers (°C) Nostril (°C) Withers (°C) Nostril (°C) Withers (°C)
Baseline 31.8 ± 2.2a 31.2 ± 2.5a 31.1 ± 2.6a 32.1 ± 1.7a 31.7 ± 1.6a 30.8 ± 2.4a
15 32.8 ± 1.1a 32.8 ± 1.3b 31.9 ± 1.5a 32.9 ± 1.4a 32.9 ± 1.6b 33.6 ± 2.1b
45 32.7 ± 0.5a 32.9 ± 1.2b 32.9 ± 0.9b 32.8 ± 1.6a 33.2 ± 1.2b 33.1 ± 1.2b
75 32.6 ± 1.0a 32.7 ± 1.0b 32.3 ± 1.6a 32.4 ± 1.9a 33.2 ± 1.2b 33.1 ± 1.0b
105 32.9 ± 0.7a 33.2 ± 1.0b 31.8 ± 1.7a 32.1 ± 1.5a 32.5 ± 1.2a 32.8 ± 1.1b
165 32.1 ± 0.9a 31.1 ± 1.4a 31.1 ± 1.4a 30.1 ± 2.1b 32.4 ± 1.7a 31.1 ± 2.6a
225 31.9 ± 1.0a 31.1 ± 1.1a 30.9 ± 1.7a 29.7 ± 1.8b 32.2 ± 1.3a 31.4 ± 2.1a
285 31.4 ± 1.0a 31.7 ± 1.3a 31.4 ± 1.2a 30.0 ± 2.0b 32.5 ± 1.1a 31.9 ± 2.1a
405 31.7 ± 0.9a 31.1 ± 1.5a 31.6 ± 1.5a 30.3 ± 1.8b 32.4 ± 0.9a 31.4 ± 2.0a
525 31.8 ± 1.0a 31.5 ± 1.6a 31.6 ± 1.8a 31.5 ± 2.1a 32.5 ± 1.8a 32.2 ± 2.1b
  1. Mean (± SD) skin temperatures in 11 horses at the withers or nostrils treated with saline, acepromazine or acepromazine + buprenorphine intravenously. Fifteen minutes before drug administration baseline measurement was performed and the first measurement was started 15 minutes after drug injection.
  2. a, b = values with different superscripts differ significantly within each treatment group (p < 0.05).