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Table 1 MeanSD) skin temperatures in 11 horses at the withers or nostrils

From: Nociceptive thermal threshold testing in horses – effect of neuroleptic sedation and neuroleptanalgesia at different stimulation sites

Medication

Saline solution

Acepromazine (0.05 mg/kg)

Acepromazine (0.05 mg/kg)/Buprenorphine (0.0075 mg/kg)

Location/ Time (min)

Nostril (°C)

Withers (°C)

Nostril (°C)

Withers (°C)

Nostril (°C)

Withers (°C)

Baseline

31.8 ± 2.2a

31.2 ± 2.5a

31.1 ± 2.6a

32.1 ± 1.7a

31.7 ± 1.6a

30.8 ± 2.4a

15

32.8 ± 1.1a

32.8 ± 1.3b

31.9 ± 1.5a

32.9 ± 1.4a

32.9 ± 1.6b

33.6 ± 2.1b

45

32.7 ± 0.5a

32.9 ± 1.2b

32.9 ± 0.9b

32.8 ± 1.6a

33.2 ± 1.2b

33.1 ± 1.2b

75

32.6 ± 1.0a

32.7 ± 1.0b

32.3 ± 1.6a

32.4 ± 1.9a

33.2 ± 1.2b

33.1 ± 1.0b

105

32.9 ± 0.7a

33.2 ± 1.0b

31.8 ± 1.7a

32.1 ± 1.5a

32.5 ± 1.2a

32.8 ± 1.1b

165

32.1 ± 0.9a

31.1 ± 1.4a

31.1 ± 1.4a

30.1 ± 2.1b

32.4 ± 1.7a

31.1 ± 2.6a

225

31.9 ± 1.0a

31.1 ± 1.1a

30.9 ± 1.7a

29.7 ± 1.8b

32.2 ± 1.3a

31.4 ± 2.1a

285

31.4 ± 1.0a

31.7 ± 1.3a

31.4 ± 1.2a

30.0 ± 2.0b

32.5 ± 1.1a

31.9 ± 2.1a

405

31.7 ± 0.9a

31.1 ± 1.5a

31.6 ± 1.5a

30.3 ± 1.8b

32.4 ± 0.9a

31.4 ± 2.0a

525

31.8 ± 1.0a

31.5 ± 1.6a

31.6 ± 1.8a

31.5 ± 2.1a

32.5 ± 1.8a

32.2 ± 2.1b

  1. Mean (± SD) skin temperatures in 11 horses at the withers or nostrils treated with saline, acepromazine or acepromazine + buprenorphine intravenously. Fifteen minutes before drug administration baseline measurement was performed and the first measurement was started 15 minutes after drug injection.
  2. a, b = values with different superscripts differ significantly within each treatment group (p < 0.05).