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Table 1 Mean incubation time of TgBoPrP mice following intracerebral inoculation of titrated bovine spongiform encephalopathy (BSE)-infected spinal cord homogenate

From: Rapid assessment of bovine spongiform encephalopathy prion inactivation by heat treatment in yellow grease produced in the industrial manufacturing process of meat and bone meals

10% Homogenate dilution

Transmission rate (diseased/total)

Mean incubation time ± SD (days)

100

100% (7/7)

242 ± 14

10–1

100% (7/7)

279 ± 12

10–2

100% (5/5)

322 ± 42

10–3

100% (6/6)

367 ± 53

10–4

33% (2/6)

736, 736, >790

10–5

17% (1/6)

735, >790

10–6

0% (0/6)

>790