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Table 1 Summary of data for dogs with DFI > 300 and DFI < 100 days, including HES1 immunohistochemistry score

From: HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors

Breed Age at Dx (yrs) Sex Tumor Loc DFI (days) Avg% stain Avg stain intensity Total score
Greyhound 4.4 MC PH 40 1 1 1
Rottweiler 5 MC DF 69 3 3 9
Greyhound 7 MC DF 77 2 1 2
Mix 9 FS T 90 2 1 2
Greyhound 8 FS PT 94 1 2 2
Labrador 10.2 FS DH 95 3 3 9
Mix 8.8 MC DF 97 2 1 2
Golden 10.8 MC PH 97 2 1 2
Mix 7.6 FS DR 307 2 2 4
Greyhound 7.1 MC PH 467 1 1 1
Mix 12.4 MC DR 694 3 3 9
Malamute 10.1 FS DR 734 3 2 6
Labrador 8.7 MC T 787 3 3 9
Golden 8 FS DR 885 3 2 6
  1. DFI disease free interval, Dx diagnosis, MC male castrated, FS female spayed, P proximal, D distal, H humerus, R radius, T tibia, Total Score is product of scores for % cells staining and staining intensity.