Figure 7

High HES1 immunoreactivity score correlates with lower histologic grade and improved outcome in canine osteosarcoma. Kaplan-Meier plot of disease free interval based on HES1 immunoreactivity score. Dogs with high HES1 scoring tumors (score ≥ 4, n = 28) had a statistically significantly longer disease free interval than dogs with low HES1 scoring tumors (score < 4, n = 33) (p = 0.0023, Log Rank test).