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Figure 6 | BMC Veterinary Research

Figure 6

From: HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors

Figure 6

Immunohistochemical analysis of nuclear HES1 protein expression in canine osteosarcoma. Examples of low (A and B, score 2) and high (C, score 6) nuclear HES1 expression in canine osteosarcomas (D is a negative control treated only with secondary antibody). Panel B shows example of a field from a low scoring tumor (based on nuclear staining) that includes scattered strong cytoplasmic staining (arrows). All photomicrographs were taken at 40× magnification; haematoxylin counterstain.

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