Figure 1

Differential expression of Notch/HES1-associated genes in canine osteosarcoma. Unbiased cluster analysis separates normal bone from tumors, but does not discriminate DFI < 100 day and DFI > 300 day primary tumors groups. An asterisk (*) and a caret (^) denote genes significantly different between tumor and normal bone (* p < 0.05, ^ q < 0.05). Genes different between DFI groups (p < 0.05) are denoted by (~). Multiple probesets are present for some genes. LOC486276 = Deltex 1 homolog (DTX1), LOC489891 = LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase/lunatic fringe (LFNG). Colored bar below indicates the intensity scale of log² transformed expression values.