Figure 1From: Expression and role of PGP, BCRP, MRP1 and MRP3 in multidrug resistance of canine mammary cancer cellsActivity of PGP, BCRP, MRP1 and MRP3. A.) Graph of mean fluorescence related to rhodamine-123 accumulation inside cancer cells obtained using FACS Aria II (Becton Dickinson, USA). Error bars refer to S.D. p < 0.05 was marked as *. One-way ANOVA followed by Tukey HSD post-hoc test was applied. B.) Representative overlay histograms of rhodamine-123 accumulation in CMT-U309 canine mammary cancer cells (control, markered as green), and treated with pgp -specific siRNA (markerd as red). The overlay histograms were created using Flowing Software (Turku University, Finland), http://www.flowingsoftware.com.Back to article page