Variable | Univariate | Multivariable* | ||||
---|---|---|---|---|---|---|
Hazard ratio | 95% CI | P | Hazard ratio | 95% CI | P | |
Tumour size | ||||||
< 3 cm | Referent | |||||
≥ 3 cm | 2.33 | 1.06-5.14 | 0.036 | NS | ||
Mode of growth | ||||||
Expansive | Referent | |||||
Invasive | 5.62 | 1.33-23.80 | 0.019 | NS | ||
MIB1 L.I. (%) | ||||||
< 40 | Referent | Referent | ||||
≥ 40 | 4.15 | 1.74-9.90 | 0.001 | 3.24 | 1.35-7.78 | 0.009 |
uPA (%) | ||||||
< 10 | Referent | |||||
≥ 10 | 3.82 | 1.14-12.72 | 0.029 | NS | ||
MMP-9 (%) | ||||||
< 50 | Referent | Referent | ||||
≥ 50 | 4.34 | 1.93-9.77 | <0.001 | 3.38 | 1.49-7.67 | 0.004 |