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Table 4 Prognostic factors significantly associated with disease free survival

From: Identification of prognostic factors in canine mammary malignant tumours: a multivariable survival study

Variable

Univariate

Multivariable*

 

Hazard ratio

95% CI

P

Hazard ratio

95% CI

P

Tumour size

      

< 3 cm

Referent

     

≥ 3 cm

2.33

1.06-5.14

0.036

  

NS

Mode of growth

      

Expansive

Referent

     

Invasive

5.62

1.33-23.80

0.019

  

NS

MIB1 L.I. (%)

      

< 40

Referent

  

Referent

  

≥ 40

4.15

1.74-9.90

0.001

3.24

1.35-7.78

0.009

uPA (%)

      

< 10

Referent

     

≥ 10

3.82

1.14-12.72

0.029

  

NS

MMP-9 (%)

      

< 50

Referent

  

Referent

  

≥ 50

4.34

1.93-9.77

<0.001

3.38

1.49-7.67

0.004

  1. *Cox regression model: forward stepwise method – likelihood ratio.
  2. NS - not significant.