Skip to main content

Table 2 Histomorphological features and RACK1 pattern in horse melanocytic lesions

From: RACK1, a clue to the diagnosis of cutaneous melanomas in horses

 

Scattera

Pigmentb

Nestingc

Circumd

Epid. Contoure

Cell sizef

Cell shapeg

Nuclear sizeh

Nuclear shapei

Nucleolar sizej

Ulcerk

RACK1 patternl

Melanocytomas

          

1

3

4

3

-

-

3

0.5

2

-

-

0

1

2

-

4

0

-

-

2

1

1

-

1

-

1

3

0

1

2

2

2

2

2

2

1

1

0

1

4

1

3

3

1

4

1.5

3

3

1.5

1

1

1

5

1

3.5

0

2

2

2

1

1

0

1

0

1

6

3

4

1

1

2

3

0.5

2

0

1

1

1

7

1

2

2

0

2

3

0

3

0

1

0

1

8

0

1

1

2

2

3

1.5

2.5

1.5

3

0

1

9

0

3

1

0

2

3

1

2

0

1

0

1

10

2

3

1

1

2

2

1.5

3

0

1

0

1

11

1

4

0

1

3

2.5

2.5

1

1

1

0

1

12

0

3.5

0

0

2

3

1.5

2

0

1

1

1

13

2

4

0

2

3

1

2

3

0

1

0

1

14

1

4

2.5

0

2

2.5

1.5

2

0

1.5

0

1

15

-

4

0

1

0

2

1.5

2

0

1

1

1

Melanomas

          

1

3

2

3

1

-

3

1

3

-

3

1

0

2

3

4

2

2

3

3

2.5

3

0

1

0

0

3

2

1

1

2

4

2

2.5

3

2

1

1

0

4

-

1

0

1

-

3

1

3

0

3

0

0

5

3

4

1

1

1

3

1

3

0

2.5

1

0

6

1

4

1

2

3

2

2

3

1.5

2

0

0

7

1

4

3

2

2

3

1

2.5

-

2

0

1

8

0

3

0

2

2

3

1

3

0

2.5

0

1

9

2

3

2

1

3

3

3

3

1

3

0

0

  1. aScatter of intraepidermal melanocytes: 0, absent; 1, slight; 2, medium; 3, prominent.
  2. bCytoplasmic pigmentation of neoplastic melanocytes: 0,absent; 1, slight; 2, medium; 3, high; 4, very high.
  3. cNesting of intraepidermal melanocytes: 0, absent; 1, slight; 2, medium; 3, prominent.
  4. dLateral circumscription: 0, discontinuous; 1, continuous; 2, abrupt.
  5. eEpidermal contour: 0, atrophy; 1, effacement; 2, normal; 3, thickening; 4, hyperplasia.
  6. fCell size: 1, small; 2, medium; 3, large.
  7. gCell shape: 0, round; 1, ovoid; 2, elongated; 3, spindled.
  8. hNuclear size: 1, small; 2, medium; 3, large.
  9. iNuclear shape: 0, round; 1, ovoid; 2, elongated; 3, spindled.
  10. jNucleolar size: 1, small; 2, medium; 3, large.
  11. kUlceration: 0, absent; 1, present.
  12. lRACK1 distribution pattern: 0, homogenous; 1, heterogenous.
  13. -: Impossible evaluation.
  14. x.5: means of two different authors observations.