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Table 1 The relation of CA 15–3 serum concentration to the clinical-pathological variables analysed

From: CA 15–3 cell lines and tissue expression in canine mammary cancer and the correlation between serum levels and tumour histological grade

   Serum CA 15–3 levels (mean ± SD) p-Value
Tumour size (cm) <2 0.70 ± 0.67 n.s.
2-5 0.84 ± 0.45 n.s.
>5 1.03 ± 0.54 n.s.
Skin ulceration Yes 0.54 ± 0.15 n.s.
No 0.91 ± 0.63 n.s.
Histopathology Simple carcinoma 0.63 ± 0.40 n.s.
Complex carcinoma 0.78 ± 0.57 n.s.
Carcinosarcoma 1.50 ± 0.28 n.s.
Inflammation Yes 0.64 ± 0.46 n.s.
No 0.90 ± 0.60 n.s.
Necrosis Yes 0.80 ± 0.59 n.s.
No 0.80 ± 0.53 n.s.
Histological grade Grade I 0.64 ± 0.36 n.s.
Grade II 1.21 ± 0.79 0.0019
Grade III 1.33 ± 0.32 0.0019
  1. Relation between tumour size, skin ulceration, histopathological diagnosis, inflammation, necrosis and histological grade of canine mammary cancer tissues and serum CA 15–3 levels. The Pearson correlation coefficient was applied using Prism version 5.00 software (GraphPad Software, USA).