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Table 3 Group composition and chronological schedule of tasks carried out in each animal

From: Vaccination prepartum enhances the beneficial effects of melatonin on the immune response and reduces platelet responsiveness in sheep

Group Composition Dose Administration
I Mock control   
II Control+Melatonin implant   
III Vaccine 2 mL subcutaneus
IV Vaccine+Melatonin implant 2 mL subcutaneus
Day 0 21 42 60 90
Vaccination + +    
Melatonin implant + +    
Blood collection + + + + +
Platelet function + + + + +
Melatonin measurement + + + + +
Rectal temperature + +    
Local reaction + +    
General reaction + +