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Table 1 Plasma melatonin concentration (pg/mL) at the time of the vaccination procedure at 10:00 A.M

From: Vaccination prepartum enhances the beneficial effects of melatonin on the immune response and reduces platelet responsiveness in sheep

Treatment    Day   
0 21 42 60 90
I. Control 123 ± 10 132 ± 12 127 ± 12 131 ± 8 126 ± 10
II. Melatonin Implant 125 ± 10 277 ± 14*† 296 ± 15*† 292 ± 12*† 261 ± 10
III. Vaccine 120 ± 14 126 ± 10 124 ± 12 128 ± 12 130 ± 10
IV. Vaccine+Melatonin Implant 126 ± 12 295 ± 11*† 328 ± 13*† 313 ± 9*† 287 ± 14*†
  1. Values represent mean melatonin concentration as determined by enzyme-linked immunosorbent assay (ELISA). Data are expressed as pg/mL and presented as mean ± S.E.M. of 10 experiments. *P < 0.05 compared with day 0. P < 0.05 compared with their respective control in non-vaccinated animals.