Study of compartmentalization in the visna clinical form of small ruminant lentivirus infection in sheep

BMC Veterinary Research

Table 2 Nucleotide and amino acid diversity, ω statistic and ancestor tissue. Nucleotide diversity, amino acid diversity, ω statistic (ratio between average number of non-synonymous substitutions per non-synonymous site, dN; and average number of synonymous substitutions per synonymous site, dS), and ancestor tissue for SRLV clones obtained from eight sheep of the Visna outbreak

Sheep No.	No. of clones	Nucleotide diversity		Amino acid diversity		dN/dS (ω)	Ancestor tissue^a
		Mean	Standard Error	Mean	Standard Error
166	90	0.0542	0.0029	0.0312	0.0017	0.690547	BAL
223	32	0.0372	0.0036	0.0333	0.0039	0.982374	PBMC
292	7	0.0035	0.0007	0.0031	0.0013	0.459471	na ^b
333	74	0.1158	0.0104	0.0496	0.0042	0.283522	PBMC
336	64	0.0659	0.0045	0.0342	0.0026	0.442547	BAL
368	43	0.0372	0.0033	0.0312	0.0024	0.722284	BAL
697	12	0.0188	0.0043	0.0179	0.0034	0.692030	na
698	28	0.0178	0.0042	0.0273	0.0041	0.346625^c	na

^a Inferences on tissue origin of most recent common ancestor were conducted only on large dataset (n > 30)
^b na: non applicable
^c dN/dS value (ω) was calculated excluding sequences with stop codons

ISSN: 1746-6148