Figure 1

Phospho-RTK array profiling of canine AGASACA and TC tumors. Shown are representative examples of phosphoprotein arrays of paired primary and metastatic AGASACA and TC using the Proteome Profiler Human Phospho-RTK Array Kit. This platform allowed simultaneous screening of 42 different RTKs. Determination of phosphorylation was based on comparison of capture antibody of interest to positive controls located on the periphery of the array. On these sample arrays, positive controls, EGFR, RET, ROR-1, and Tie-1 have been identified for comparison