Differential 2-DE analysis of sheep serum during peripartum. A) 2-DE serum sheep map and expanded view of the gel portions including the deregulated proteins during peripartum. Spot proteins differing by > 2 fold (P < 0.05) in sheep at lambing (lambing), 15 days after lambing (+15 days) compared to sheep two months before lambing (basal) were indicated. Area 1: spots identified as Hp; Area 2: spots identified as α1AGP; Area 3: spots identified as Apo A-1; Area 4: a spot identified as TTR. B) Histograms representing log fold change (calculated as a ratio of average density spots at lambing and +15 days vs basal). *: Spots with fold change more than 2 or less than 0.5 with statistically significant P < 0.05. Black and grey bars correspond to lambing vs basal and +15 vs basal respectively.