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Table 7 Responses of pigs to vaccination with O/HN/CHA/93 and rM-HN vaccines and O/JX/CHA/2010 challenge

From: Evaluation of a genetically modified foot-and-mouth disease virus vaccine candidate generated by reverse genetics

Vaccinea

Pig no.

VNT titer versus O/JX/CHA/2010b

Response to challenge with O/JX/CHA/2010

Vaccinea

Pig no.

VNT titer versus O/JX/CHA/2010b

Response to challenge with O/JX/CHA/2010

Lesionsc

3ABCd

Lesionsc

3ABCd

O/HN/CHA/93

501

1.6

-

-

rM-HN

601

1.9

-

-

502

2.3

-

-

602

2.1

-

-

503

1.7

-

-

603

1.6

-

-

504

2.0

-

-

604

1.7

-

+

505

1.9

-

-

605

2.0

-

-

506

2.0

-

-

606

1.8

-

-

507

2.2

-

-

607

2.0

-

-

508

1.7

-

+

608

2.1

-

-

509

2.1

-

-

609

1.7

-

-

510

1.8

-

-

610

2.0

-

-

511

2.1

-

-

611

1.7

-

-

512

1.9

-

-

612

2.0

-

-

513

1.6

-

-

613

1.9

-

-

514

1.8

-

-

614

1.8

-

-

515

1.6

-

-

615

1.7

-

-

516

2.2

-

-

616

1.7

-

-

Control

517

<1.0

++

+

Control

617

<1.0

++

+

 

518

<1.0

++

+

 

618

<1.0

++

+

  1. a,b,c,d. described as above.