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Table 2 Characteristics of experiment 2

From: Carprofen for perioperative analgesia causes early anastomotic leakage in the rat ileum

 

Administration of carprofen from day 0

Administration of carprofen from day 1

Administration of carprofen from day 2

Day of termination

3

4

5

Number operated at day 0

15

15

15

Premature death (day)

0

2 (3,3)

0

Anastomotic leakage

12

7

3(p = 0.0028)

  1. After termination 12 animals in each group were analysed for wound strength and the remaining animals for histology. Signs of anastomotic leakage were noted at obduction. P-value denotes a significant difference with the group administered carprofen from day 0 (Fisher’s two-sided test).