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Table 4 Immunofluorescence score (IF), microscopic and macroscopic lung lesion score (LLS)1

From: Vaccination reduces macrophage infiltration in bronchus-associated lymphoid tissue in pigs infected with a highly virulent Mycoplasma hyopneumoniaestrain

 

IF

Microscopic LLS

Macroscopic LLS

Scores

(0-3)

(0-5)

(0-35)

Weeks PI

4

8

4

8

4

8

control

0.00 ± 0.00a

0.00 ± 0.00a

1.17 ± 0.08a

1.17 ± 0.13a

0.00 ± 0.00a

0.00 ± 0.00a

nvLV

0.77 ± 0.20a, b

1.33 ± 0.20b, c

2.90 ± 0.26b

2.92 ± 0.15b

2.38 ± 1.20a, b

1.20 ± 0.30a

nvHV

1.26 ± 0.27b

1.44 ± 0.28b

4.04 ± 0.15c

3.62 ± 0.15b

6.69 ± 1.70b

5.60 ± 1.20b

vLV

0.90 ± 0.21a, b

1.33 ± 0.13b, c

3.10 ± 0.16b

3.41 ± 0.17b

0.93 ± 0.90a

1.74 ± 0.40a

vHV

0.80 ± 0.11a, b

0.67 ± 0.14a, c

3.02 ± 0.09b

3.35 ± 0.07b

0.11 ± 0.07a

1.99 ± 0.60a

  1. nv non-vaccinated; v vaccinated; LV low virulent challenge strain; HV highly virulent challenge strain
  2. 1 Scoring was performed in vaccinated and non-vaccinated pigs at 4 and 8 weeks after endotracheal inoculation with a low or highly virulent M. hyopneumoniae strain. A non-vaccinated and non- infected control group was also included. The parameters were determined in the study of Villarreal et al. (2011) [11] and included in the statistical analysis of the present study.