Vaccination reduces macrophage infiltration in bronchus-associated lymphoid tissue in pigs infected with a highly virulent Mycoplasma hyopneumoniaestrain

Table 3 Spearman correlation coefficients between the different parameters investigated in this study¹

		Log qPC R	T- lymphocytes	B- lymphocytes	Macrophages	IF	Micro LLS	Macro LLS
Antibody titer	0	-0.06	-0.06	-0.31	-0.52*	0.17	-0.02	-0.34*
		0.24	-0.09	-0.03	-0.49*	0.17	0.26	0.19
weeks PI	2	0.13	0.02	-0.31	-0.53*	0.03	0.01	-0.26
		0.33*	0.19	0.13	-0.37	0.15	0.33*	0.22
	4	0.20	0.02	-0.11	-0.19	0.17	0.25	-0.01
		0.27	0.32	0.22	-0.29	0.01	0.45**	0.20
	6	-	-	-	-	-	-	-
		0.38*	0.57*	0.42	-0.07	0.08	0.41**	0.25
	8	-	-	-	-	-	-	-
		0.43**	0.68**	0.52*	-0.04	0.12	0.46**	0.29
Log qPCR			0.33	0.48*	0.63*	0.08	0.62**	0.52**
			0.33	0.36	0.45	0.30*	0.28	0.39*
T- lymphocytes				0.40	0.30	0.15	0.24	0.50*
				0.83**	0.37	0.15	0.66**	0.60*
B- lymphocytes					0.76**	0.02	0.56**	0.50*
					0.39	0.26	0.55**	0.53*
Macrophages						-0.02	0.67**	0.67**
						0.24	0.11	-0.04
IF							0.24	0.13
							0.31*	0.44**
Micro LLS								0.67**
								0.43**

* p < 0.05; ** p < 0.01
¹ antibody titer (SP ratio of the serology), the scoring of immune cells (T-lymphocytes, B-lymphocytes and macrophages), immunofluorescence staining for M. hyopneumoniae (IF) and the microscopic and macroscopic lung lesion score (LLS) at the level of the individual pig at 4 (top) and 8 (bottom) weeks post-infection

ISSN: 1746-6148