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Table 3 Clinical scores and severity of enophthalmos in different treatment groups on admission and 24 hours after the initiation of therapy

From: Construction and validation of a decision tree for treating metabolic acidosis in calves with neonatal diarrhea

   Group I: Group II: Group III: Group IV: Group V:
Oral rehydration Constant drip infusion Short-term infusion Constant drip infusion Constant drip infusion
250 mmol NaHCO3 500/750 mmol NaHCO3 500 mmol NaHCO3 750 mmol NaHCO3
n = 20 n = 47 n = 10 n = 34/29 (0 h/24 h) n = 10
Posture (score 1–7) 0 h 2 (1–3)NC 2 (1–3)NC 4.5 (4–6)NC 5 (4–5)NC 6 (6–7)NC
24 h 2 (1–2)IV 2 (1–3) 2 (1–2) 2 (2–4)I 2 (2–3)
Behavior (score 1–5) 0 h 1 (1–3)NC 2 (1–3)NC 3 (2–4)NC 3 (3–4)NC 4 (3–5)NC
24 h 1 (1–3) 2 (1–2) 2 (1–3) 2 (1–3) 2 (1–3)
Suckling reflex (score 1–3) 0 h 1 (1–2)NC 2 (1–3)NC 2 (1–3)NC 3 (1–3)NC 3 (2–3)NC
24 h 2 (1–3) 2 (1–3) 2 (1–2) 2 (1–3) 2 (1–3)
Palpebral reflex (score 1–4) 0 h 1 (1–2)NC 1 (1–3)NC 3 (2–4)NC 2.5 (1–4)NC 3.5 (1–4)NC
24 h 1 (1–2) 1 (1–2)III,V 2 (1–3)II 1 (1–2) 1 (1–2)II
Degree of enophthalmos (score 1–4) 0 h 1 (1–1)NC 2 (1–4)NC 1 (1–1)NC 3 (1–4)NC 3 (2–4)NC
24 h 1 (1–3) 1 (1–3) 1 (1–1) 1 (1–3) 1 (1–2)
Degree of skin tenting (score 1–4) 0 h 2 (1–3)NC 3 (1–4)NC 3 (1–3)NC 4 (2–4)NC 4 (3–4)NC
24 h 2 (1–4) 2 (1–4) 2 (1–3) 2 (1–3) 2.5 (1–4)
Severity of enophthalmos (mm) 0 h 1 (0–3)NC 4 (1–10)NC 2 (1–3)NC 6 (3–12)NC 6.5 (4–11)NC
  24 h 1 (0–6) 1 (1–6) 1 (1–2) 1 (0–6) 2 (0–4)
  1. Values are given as medians and corresponding ranges (minimum - maximum). Bold median values indicate statistically significant changes during the investigation period. Five out of 34 calves of treatment group IV had to be treated alternatively for reasons of expected treatment failure. Comparisons between times of examination were performed for the remaining 29 calves of this group. Superscripts indicate number of groups with significantly different values after pairwise comparisons. Since grouping of calves was based on clinical findings and most of the given parameters are closely correlated with each other the initial values were not compared (indicated by NC).