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Table 1 Improvement of clinical signs during the study period as indicated by the number of calves in the clinical categories on admission (n = 121) and 24 hours after the initiation of therapy (n = 116)

From: Construction and validation of a decision tree for treating metabolic acidosis in calves with neonatal diarrhea

Clinical Categories (Score)

On admission*

After 24 h

p value

n

n

Posture/Ability to stand

 Standing up by itself (1)

7

12

< 0.001

 Standing up after encouragement (2)

53

99

 Standing securely after lifting (3)

7

4

 Insecurely, able to correct position if pushed (4)

14

1

 Insecurely, not able to correct position if pushed (5)

24 (29)

-

 Sternal recumbency (6)

7

-

 Lateral recumbency (7)

4

-

Behavior

 Adequate reaction to acoustic and optical stimuli, very bright and alert (1)

18

48

< 0.001

 Adequate reaction to acoustic and optical stimuli (2)

37

62

 Delayed reaction to acoustic and optical stimuli (3)

42

6

 Calf reacts only to painful stimuli (e.g. venipuncture) (4)

15 (20)

-

 No reaction to painful stimuli (5)

4

-

Suckling reflex

 Strong (1)

33

45

0.003

 Weak (2)

42

52

 Absent or chewing movements (3)

41 (46)

19

Palpebral reflex

 Eyelids are closed immediately and fully (1)

55

98

< 0.001

 Eyelids are closed immediately but not fully (2)

34

17

 Eyelids are closed with delay and not fully (3)

20 (24)

1

 Eyelids are not closed at all (4)

7 (8)

-

Degree of enophthalmos #

 None (1)

41

99

< 0.001

 Slightly sunken (2)

31 (32)

13

 Moderately sunken (3)

26 (29)

4

 Severely sunken (4)

18 (19)

-

Degree of skin tenting

 Resolution of skin tenting prompt (1)

8

35

< 0.001

 Slightly delayed (2)

23

45

 Moderately delayed (3)

38 (40)

32

 Skin tenting does not resolve spontaneously (4)

47 (50)

4

 
  1. *Including calves that were not treated with the decision tree for reasons of expected treatment failure are indicated by brackets.
  2. # The bulbi were classified as sunken in cases of a visible gap between the eyeball and caruncula lacrimalis. The median measured eyeball recession (mm) in the four categories were 1, 4, 6, and 9, respectively.