Skip to main content

Table 3 PMCA amplification in an ARQ/VRQ substrate

From: In vitro amplification of ovine prions from scrapie-infected sheep from Great Britain reveals distinct patterns of propagation

Seed

Substrate

VRQ/VRQ#

ARQ/ARQ#

ARQ/VRQ1*

ARQ/VRQ2*

ARQ/VRQ3*

VRQ/VRQ1

+

-

+/+/+/+

+/+/+/+

+/+/+/+

ARQ/ARQ1

-

+

−/−/−/−

−/−/−/−

+/−/−/−

  1. *For each of the amplifications performed using the heterozygous substrates four different scrapie sources were used and tested once in each of the substrates.
  2. #The control amplifications performed in homozygous substrates used only one of these seeds. +/− symbols show the amplification outcome for each animal.