Changes over time in craniocerebral morphology and syringomyelia in cavalier King Charles spaniels with Chiari-like malformation

Table 1 Summary of clinical complaint at presentation and treatments

Case Details		First Scan		Scan interval (months)	Second Scan		Change in SM lesion width (mm)
No.	Age (months)/sex	Clinical complaint	Treatment	Scan interval (months)	Clinical complaint²	Treatment	Change in SM lesion width (mm)
1	78/female neutered	Cervical hyperaesthesia Ataxia	Carprofen	42	Poor control of original complaint	Prednisolone	0
2	59/male neutered	Dysaesthetic behaviour¹	Gabapentin	5	Poor control of original complaint	Gabepentin	1.4
3	13/male neutered	Dysaesthetic behaviour¹	Gabapentin	17	Poor control of original complaint	Prednisolone	0
4	74/male neutered	Cervical hyperaesthesia	Gabapentin	3	Dysaesthetic behaviour¹	Pregabalin	0.1
5	6/female	Dysaesthetic behaviour¹ Ataxia	Meloxicam Gabapentin	83	Recurrent generalised seizures	Phenobarbitone Gabapentin Meloxicam	3.5
6	51/male neutered	Cervical hyperaesthesia	Acetazolamide Meloxicam	6	Poor control of original complaint	Acetazolamide Gabapentin	0.3
7	15/male	Seizures	Phenobarbitone	20	Recurrent generalised seizures	Phenobarbitone Levetiracetam	2.2
8	67/male neutered	Cervical hyperaesthesia Head tilt Ataxia	Clindamycin	4	Complex partial seizures	Phenobarbitone	0
9	24/female	Cervical hyperaesthesia	None	11	Recurrent generalised seizures	Potassium Bromide	2.7
10	6/male	Cervical hyperaesthesia	Carprofen	37	Migrating foreign body	Carprofen Prednisolone Trimethoprin-sulphonamide	1.4
11	90/male neutered	Facial paresis	Potentiated amoxcillin Meloxicam	3	Head tilt	Enrofloxacin	0.4
12	48/female neutered	Cervical hyperaesthesia	Gabapentin	8	Complex partial seizures	Potassium Bromide	0

Dysaesthetic behaviour included phantom scratching and facial rubbing.
Clinical complaints considered not attributable to CM/SM included seizures, head tilt, facial paresis and migrating foreign bodies.

ISSN: 1746-6148