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Table 2 Haematological indices of broiler-chicks given varying doses of crude extract of Loxostylis Alata in the toxicity study

From: A controlled study to determine the efficacy of Loxostylis alata (Anacardiaceae) in the treatment of aspergillus in a chicken (Gallus domesticus) model in comparison to ketoconazole

Haematology Units Dose administered (mg/kg)
   Control (DMSO ml/kg) 50 200 300
Haemoglobin (Hb) g/dl 143.33 ± 4.7 139.33 ± 0.88 144.67 ± 8.66 135.50 ± 1.50
Red cell count (RCC) x1012/L 2.62 ± 0.12 2.50 ± 0.11 2.83 ± 0.09 2.40 ± 0.02
HT (haematocrit) l/l 0.36 ± 0.01 0.34 ± 0.01 0.33 ± 0.03 0.30 ± 0.01
Mean cell volume (MCV) Fl 140.00 ± 2.95 135.67 ± 1.77 126.33 ± 6.90 135.00 ± 1.00
Mean cell haemoglobin (MCH) Pg 54.77 ± 0.84 54.17 ± 0.54 51.40 ± 3.22 55.10 ± 0.35
Mean cell haemoglobin concentration (MCHC) g/dl 39.27 ± 0.23 39.23 ± 0.84 40.87 ± 0.63 40.90 ± 0.05
Red cell distribution width (RDW)   13.47 ± 0.923 12.47 ± 0.67 14.77 ± 1.76 13.70 ± 1.15
White cell count (WCC) x109/L 3.73 ± 0.95 5.33 ± 1.09 19.80 ± 8.06a 4.40 ± 0.80
Absolute neutrophil (total) x109/L 1.31 ± 0.26 1.94 ± 0.47 10.31 ± 4.77a 2.30 ± 0.45
Absolute neutrophil (matured) x109/L 1.31 ± 0.26 1.94 ± 0.47 10.31 ± 4.77a 2.30 ± 0.45
Absolute neutrophil (immatured) x109/L 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00
Absolute lymphocyte x109/L 1.99 ± 0.50 2.56 ± 0.49 6.25 ± 1.66a 1.50 ± 0.34
Absolute monocyte x109/L 0.35 ± 0.15 0.34 ± 0.05 1.83 ± 1.40 0.40 ± 0.16
Absolute eosinophil x109/L 0.00 ± 0.00 0.27 ± 0.11 0.88 ± 0.03 0.1 ± 0.03
Absolute basophil x109/L 0.09 ± 0.06 0.07 ± 0.04 0.42 ± 0.02 0.00 ± 0.00
  1. Means with superscript letter differ significantly (p ≤ 0.05) from the control.
  2. N=3, except the 300mg group where one of the chicks died 4-days p.t.
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BMC Veterinary Research

ISSN: 1746-6148

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