Profiles of the serum cytokine and chemokine concentrations in Reston virus-infected cynomolgus macaques. The serum concentrations of IFN-γ, IL-8, IL-12, MIP1α, and IL-1ra. The concentrations of these proinflammatory cytokines/chemokines (IFN-γ, IL-8, IL-12, MIP1α) and the anti-inflammatory cytokine (IL-1ra) were significantly higher in convalescent (Ag - NT +) than in non-convalescent sera (Ag + NT -). Each dot represents one sample, and dashes (-) represent the median values. * indicates p < 0.05, ** indicates p < 0.005 (Mann Whitney test). Broken lines and the numbers written aside indicate the average concentrations of cytokine and chemokine in negative control cynomolgus macaques (n = 13).