Effect of analgesic therapy on clinical outcome measures in a randomized controlled trial using client-owned dogs with hip osteoarthritis

Table 8 Effect of analgesic treatment on gait kinetics measured using a force-plate

Kinetic parameters	ABT-116 (n = 12)	Carprofen (n = 11)	Tramadol (n = 9)	Placebo (n = 9)
Peak Vertical Force	4.4 ± 6.8	1.2 ± 7.5	2.1 ± 4.9	2.8 ± 10.6
Statistical Power	0.07	0.07	0.05
Sample Size for Power > 0.8	485	445	>1000
Peak Vertical Impulse	2.3 ± 13.4	2.4 ± 7.1	−1.1 ± 6.9	−1.8 ± 6.9
Statistical Power	0.14	0.24	0.05
Sample Size for Power > 0.8	100	45	>1000
Falling Slope	−3.2 ± 19.0	−0.6 ± 16.2	4.6 ± 19.5^a	11.1 ± 35.2^a
Statistical Power	0.10	0.14	0.08
Sample Size for Power > 0.8	185	95	275

Note: Data represent percentage change in Week 3 of the trial, when compared with mean baseline. Power analysis results compare each treatment group with placebo. ^aFalling slope is more negative after treatment (undesirable effect).

ISSN: 1746-6148