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Table 4 Effect of analgesic treatment on canine brief pain inventory (CBPI) questionnaire scores

From: Effect of analgesic therapy on clinical outcome measures in a randomized controlled trial using client-owned dogs with hip osteoarthritis

 

ABT-116 (n = 13)

Carprofen (n = 12)

Tramadol (n = 12)

Placebo (n = 12)

Total CBPI Score

−20.3 ± 39.5

−40.6 ± 34.9**

−38.5 ± 30.0***

−13.5 ± 42.7

Statistical Power

0.07

0.37

0.36

 

Sample Size for Power > 0.8

n = 580

n = 34

n = 35

 

Pain Severity Score

−15.3 ± 45.0

−39.4 ± 34.5**

−24.9 ± 39.0

−14.7 ± 43.7

Statistical Power

0.05

0.32

0.19

 

Sample Size for Power > 0.8

n > 1,000

n = 41

n = 260

 

Pain Interference Score

−20.1 ± 44.8

−41.8 ± 37.3**

−47.2 ± 29.2***

−12.6 ± 44.4

Statistical Power

0.07

0.39

0.60

 

Sample Size for Power > 0.8

n = 500

n = 32

n = 19

 
  1. Note: Data represent percentage change in Week 3 of the trial, compared with mean baseline. Power analysis results compare each treatment group with placebo. Significance of changes in questionnaire scoring from mean baseline to end of the trial is indicated as follows: ** - P ≤ 0.01; *** - P ≤ 0.001.