Effect of analgesic therapy on clinical outcome measures in a randomized controlled trial using client-owned dogs with hip osteoarthritis

Table 2 Plasma concentrations of ABT-116, carprofen, tramadol, and placebo before and after the first and last doses of the treatment period

Note: All values represent mean ± standard deviation in ng/ml. n – sample number. ^#One dog in the treatment group was excluded because high drug concentrations were detected in the pre-treatment sample and low concentrations in one or more post-treatment samples. ABT-116, Carprofen, and Tramadol were not detected in any plasma sample from the Placebo group. Significance of changes in plasma drug concentrations from post-treatment sample on Day 8 is indicated as follows: ** - P < 0.01; *** - P < 0.001.

ISSN: 1746-6148