Reliability of quantitative echocardiography in adult sheep and goats

BMC Veterinary Research

Table 2 Cardiac dimensions, time indices, technique and measurement reliability from 51 adult healthy sheep

Parameter	Reference range (mean±2SD)	Mean±SD	Technique repeatability		Technique reproducibility			Measurement repeatability		Measurement reproducibility
Parameter	Reference range (mean±2SD)	Mean±SD	Max% difference	ICC	Max% difference	ICC	Kappa	Max% difference	ICC	Max% difference	ICC	Kappa
PA (cm) + *	1.96-2.80	2.38±0.21	2.5	0.92	3.8	0.88	0.87	2.3	0.94	2.8	0.91	0.89
Ao (cm) + *	2.24-3.24	2.74±0.25	2.9	0.90	4.2	0.86	0.85	2.6	0.92	3.1	0.88	0.89
PA: Ao	0.77-1.01	0.89±0.06
AoS (cm)	2.58-3.82	3.20±0.31	3.2	0.90	3.0	0.90	0.88	2.8	0.92	3.2	0.89	0.87
Ao-cs (cm)	2.49-3.69	3.09±0.30	2.7	0.93	3.6	0.88	0.87	2.4	0.94	2.8	0.90	0.90
LAD (cm)+	2.83-6.35	4.59±0.88	2.6	0.91	4.1	0.84	0.82	2.2	0.94	2.7	0.89	0.88
ET (sec)	0.11-0.27	0.19±0.04	3.1	0.90	3.3	0.89	0.87	2.4	0.93	2.6	0.92	0.91
PEP (ms)	0.01-0.05	0.03±0.01	2.8	0.88	3.0	0.87	0.96	2.6	0.92	2.9	0.90	0.92
EPSS (cm)	0.24-0.60	0.42±0.09	3.3	0.85	3.7	0.82	0.80	2.7	0.90	3.0	0.92	0.86
RVDd (cm)	0.70-2.14	1.42±0.36	5.9	0.66	7.2	0.51	0.56	3.4	0.84	4.4	0.74	0.64
RVDs (cm)	0.56-1.12	0.84±0.14	6.2	0.72	6.6	0.57	0.59	3.6	0.82	4.1	0.72	0.66
IVSd (cm) + *	0.89-1.49	1.19±0.15	3.8	0.84	3.6	0.82	0.84	2.8	0.91	3.2	0.87	0.85
IVSs (cm)+	1.19-1.91	1.55±0.18	4.2	0.82	3.8	0.82	0.84	3.0	0.90	3.5	0.88	0.88
LVDd (cm)+	3.34-5.50	4.42±0.54	2.4	0.91	2.7	0.90	0.89	2.2	0.93	2.5	0.90	0.88
LVDs (cm)*	1.92-3.32	2.62±0.35	2.8	0.92	3.2	0.90	0.88	2.5	0.94	2.6	0.92	0.90
FWd (cm) + *	0.71-1.27	0.99±0.14	4.8	0.82	5.7	0.76	0.74	3.4	0.84	3.9	0.79	0.78
FWs (cm)*	0.94-2.06	1.50±0.28	5.2	0.81	6.3	0.74	0.73	3.6	0.86	4.1	0.81	0.80
FS (%)	30.6-49.8	40.2±4.8
LVEF (%)	67.1-86.7	76.9±4.9
HR (bpm)	73.5-95.1	84.3±5.4

Table 2 Reference ranges (mean± 2 standard deviations) and mean ± standard deviation for cardiac dimensions, time indices and heart rate from 51 adult healthy sheep. Technique and measurement repeatability and reproducibility are also displayed and assessed using intra-class correlation coefficients (ICC) and maximal differences between measures. Cohen’s Kappa was additionally used to assess reproducibility. * shows significant species differences and ⁺ shows significant differences when corrected for bodyweight; p < 0.05. Abbreviations: Ao: aorta; Ao-cs: aorta measured from a short axis view (cross-section); AoS: aortic sinus; EPSS: e-point to septal separation; ET: ejection time; FS: fractional shortening; FWd: left ventricular free wall measured in diastole; FWs: left ventricular free wall measured in systole; HR: heart rate; IVSd: inter-ventricular septum measured in diastole; IVSs: inter-ventricular septum measured in systole; LAD: left atrial diameter measured end systole; LVDd: left ventricular diameter measured in diastole; LVDs: left ventricular diameter measured in systole; LVEF: left ventricular ejection fraction; PA: pulmonary artery PA: Ao: ratio of pulmonary artery to aorta; PEP: pre-ejection period; RVDd: right ventricular diameter measured in diastole; RVDs: right ventricular diameter measured in systole.

ISSN: 1746-6148