Table 2 Up/down-regulated genes in canine mammary cancer cell lines grown as co-culture with macrophages
No. | Fold change | Gene symbol | Gene name |
|---|---|---|---|
1 | ↑3.25 | ANPEP | Aminopeptidase N |
2 | ↑3.83 | ATP6V0E1 | V-type proton ATPase subunit e 1 |
3 | ↑4.98 | C5AR1 | C5a anaphylatoxin chemotactic receptor |
4 | ↑4.86 | CCL2 | C-C motif chemokine 2 |
5 | ↑5.23 | CCL3 | C-C motif chemokine 3 |
6 | ↑4.28 | CCL4 | C-C motif chemokine 4 |
7 | ↑3.99 | CCL5 | C-C motif chemokine 5 |
8 | ↑3.91 | CCL8 | C-C motif chemokine 8 |
9 | ↑3.03 | CCR1 | CCR1 |
10 | ↑3.66 | CCR5 | C-C chemokine receptor type 5 |
11 | ↑4.47 | CD163 | Soluble CD163 |
12 | ↑3.55 | CD40 | Tumor necrosis factor receptor superfamily member 5 |
13 | ↑4.89 | CD80 | CD80 |
14 | ↑4.31 | CD86 | CD86 |
15 | ↑3.38 | COX17 | Cytochrome c oxidase copper chaperone |
16 | ↑3.62 | CSF2 | Granulocyte-macrophage colony-stimulating factor |
17 | ↑3.53 | CSF3 | Granulocyte colony-stimulating factor |
18 | ↑3.68 | CSF1R | Colony stimulating factor receptor 1 |
19 | ↑3.09 | CTSC | Dipeptidyl-peptidase 1 light chain |
20 | ↑5.06 | CTSK | Cathepsin K |
21 | ↑5.92 | CTSS | Cathepsin S |
22 | ↑3.5 | CXCR7 | C-X-C chemokine receptor type 7 |
23 | ↑3.26 | DLA-64 | DLA-64 |
24 | ↑3.26 | EMR1 | EMR1 |
25 | ↑3.31 | FTH1 | Ferritin heavy chain |
26 | ↑3.1 | FTL | Ferritin light chain |
27 | ↑5.25 | IL1A | Interleukin-1 alpha |
28 | ↑5.07 | IL1B | Interleukin-1 beta |
29 | ↑3.45 | IL6 | Interleukin-6 |
30 | ↑5.6 | IL8 | Interleukin-8 |
31 | ↑3.09 | MMP9 | Matrix metalloproteinase-9 |
32 | ↑4.83 | MX1 | Interferon-induced GTP-binding protein Mx1 |
33 | ↑3.34 | NPC2 | Epididymal secretory protein E1 |
34 | ↑3.19 | OOEP | Oocyte-expressed protein |
35 | ↑3.6 | PLA2G7 | Platelet-activating factor acetylhydrolase |
36 | ↑3.23 | PSAP | Pulmonary surfactant-associated protein A |
37 | ↑4.84 | PSMB8 | Proteasome subunit beta type-8 |
38 | ↑3.57 | PSMB9 | Proteasome subunit beta type |
39 | ↑3.74 | PTGES | Prostaglandin E synthase |
40 | ↑3.35 | SLAMF1 | Signaling lymphocytic activation molecule |
41 | ↑3.34 | SYK | SYK |
42 | ↑4.64 | TLR2 | Toll-like receptor 2 |
43 | ↑3.55 | TLR4 | TLR4 |
44 | ↓3.11 | RXRB | Retinoic acid receptor RXR-beta |
45 | ↓3.17 | SLC5A3 | Sodium/myo-inositol cotransporter |
46 | ↓3.06 | MSX2 | Homeobox protein MSX-2 |
47 | ↓5.17 | KRT13 | Keratin 13 |