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Table 2 Mean peak serum cortisol concentrations (Cmax), time to peak concentration (Tmax) and area under the time-effect curve (AUEC) for cortisol determined using non-compartmental analysis

From: Pharmacokinetics and effect of intravenous meloxicam in weaned Holstein calves following scoop dehorning without local anesthesia

Cortisol parameters Control Meloxicam P value
Tmax (min) 15.83 ± 4.92 19.17 ± 9.17 0.68
Cmax (nmol/L) 159.17 ± 11.032 165.00 ± 14.84 0.76
AUEC minutenmol/L 133,584 ± 18,039 122,961 ± 20,441 0.70
  1. Cmax Peak cortisol concentrations.
  2. Tmax time to peak cortisol concentration.
  3. AUEC area under the time-effect curve for cortisol determined using non-compartmental analysis.