Obesity-related metabolic dysfunction in dogs: a comparison with human metabolic syndrome

BMC Veterinary Research

Table 2 Pre- and post-weight-loss metabolic biomarkers in the study dogs

Criterion	Pre-weight loss	Post-weight loss	P ¹
BCS ¹	8 (7-9)	5 (4-6)	<0.001
SBP ² (mmHg)	155 (108-220)	130 (105-180)	0.008
Cholesterol (mmol/L)	5.6 (2.5-9.3)	5.0 (1.9-7.7)	0.003
Triglycerides (mmol/L)	1.2 (0.6-5.3)	0.9 (0.1-2.1)	0.018
Glucose (mmol/L)	5.4 (3.5-8.7)	5.2 (3.0-7.4)	0.166
Insulin (pmol/L)	256 (36-687)	135 (24-626)	<0.001
Adiponectin (μg/mL)	7.8 (0.8-19.5)	8.0 (1.1-34.9)	0.001
hsCRP (nmol/L)	9.1 (0.1-225.5)	9.1 (0.0-193.6)	0.822

Results are expressed as median (range). ¹ Body condition score assessed with a 9-integer scale [19]. ² Systolic blood pressure, measured indirectly by an oscillometric technique. ³ Urine protein:creatinine ratio. For UPCR, due to lack of availability of urine samples, was measured on 30/35 dogs. All results are expressed as mean, median (range) & number above upper limit; the exception is except for body condition score (BCS), where the mean values are not reported as the data were categorical. hsCRP: high-sensitivity C-reactive protein.

ISSN: 1746-6148