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Table 8 Relative expression level of IL-15 and IL-18 genes in inoculated SPF chickens compared to control SPF chickens

From: Co-administration of avian influenza virus H5 plasmid DNA with chicken IL-15 and IL-18 enhanced chickens immune responses

DNAs inoculated groups Trial 1 Trial 2
IL-15 IL-18 IL-15 IL-18
Control 0.62 ± 0.10 0.13 ± 0.03 0.41 ± 0.07 0.10 ± 0.02
pDisplay 0.41 ± 0.05 0.11 ± 0.03 0.51 ± 0.02 0.15 ± 0.00
pDis/H5 1.38 ± 0.11* b 0.14 ± 0.06 1.20 ± 0.13* b 0.17 ± 0.03
pDis/H5 + pDis/IL-15 3.69 ± 0.51* a c 0.19 ± 0.05 3.53 ± 0.33* a 0.18 ± 0.04
pDis/H5 + pDis/IL-18 0.74 ± 0.06 0.45 ± 0.02* b c 0.95 ± 0.12* 0.69 ± 0.13* b c
  1. Note: Each value represents the mean ± SD. Statistically significant differences (P < 0.05) are indicated by an asterisk (*), treated compared with untreated groups; a, pDis/H5 compared with pDis/H5 + pDis/IL-15; b, pDis/H5 compared with pDis/H5 + pDis/IL-18; c, pDis/H5 + pDis/IL-15 compared with pDis/H5 + pDis/IL-18.