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Table 8 Relative expression level of IL-15 and IL-18 genes in inoculated SPF chickens compared to control SPF chickens

From: Co-administration of avian influenza virus H5 plasmid DNA with chicken IL-15 and IL-18 enhanced chickens immune responses

DNAs inoculated groups

Trial 1

Trial 2

IL-15

IL-18

IL-15

IL-18

Control

0.62 ± 0.10

0.13 ± 0.03

0.41 ± 0.07

0.10 ± 0.02

pDisplay

0.41 ± 0.05

0.11 ± 0.03

0.51 ± 0.02

0.15 ± 0.00

pDis/H5

1.38 ± 0.11* b

0.14 ± 0.06

1.20 ± 0.13* b

0.17 ± 0.03

pDis/H5 + pDis/IL-15

3.69 ± 0.51* a c

0.19 ± 0.05

3.53 ± 0.33* a

0.18 ± 0.04

pDis/H5 + pDis/IL-18

0.74 ± 0.06

0.45 ± 0.02* b c

0.95 ± 0.12*

0.69 ± 0.13* b c

  1. Note: Each value represents the mean ± SD. Statistically significant differences (P < 0.05) are indicated by an asterisk (*), treated compared with untreated groups; a, pDis/H5 compared with pDis/H5 + pDis/IL-15; b, pDis/H5 compared with pDis/H5 + pDis/IL-18; c, pDis/H5 + pDis/IL-15 compared with pDis/H5 + pDis/IL-18.