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Table 4 HI titer of serum samples obtained from chickens inoculated with various plasmid DNAs in Trial 1

From: Co-administration of avian influenza virus H5 plasmid DNA with chicken IL-15 and IL-18 enhanced chickens immune responses

DNAs- inoculated groups    HI titer   
Weeks post inoculation
1 2* 3 4 5 6 7
Control 0 0 0 0 0 0 0
pDisplay 0 0 0 0 0 0 0
pDis/H5 1.52 ±1.38 1.62 ±1.43 1.87 ±1.43 2.30 ±1.34 3.25 ±1.60 4.92 ±1.60 6.50 ±1.40
pDis/H5 + pDis/IL-15 1.52 ±1.43 1.62 ±1.60 5.28 ±1.43a c 6.50 ±1.40a 13.00 ±1.40a c 10.56 ±1.43a c 12.13 ±1.43a c
pDis/H5 + pDis/IL-18 1.52 ±1.43 2.30 ±1.55 3.25 ±1.40b 4.92 ±1.40b 6.50 ±1.40b 6.50 ±1.40 6.50 ±1.40
  1. * Chickens were given a booster 2 weeks after initial inoculation. Statistically significant differences (P < 0.05) are indicated by a, pDis/H5 compared with pDis/H5 + pDis/IL-15; b, pDis/H5 compared with pDis/H5 + pDis/IL-18; c, pDis/H5 + pDis/IL-15 compared with pDis/H5 + pDis/IL-18.