Summary of the trial design and inclusion of dogs. Forty dogs, with exocrine pancreatic insufficiency, were randomised to receive one of two enzyme treatments (test e.g. coated and control e.g. uncoated), and were re-examined at 3 follow-up visits (day 14, day 28 and day 56). Information in the lower part of the figure refers to the procedures conducted at each visit. BCS: body condition score; LTFU: lost to follow up. Arrows indicate when doses of parenteral cobalamin were injected. Other than the timeline, all numbers refer to dogs recruited and remaining within the trial at the respective points.