TY - JOUR AU - Kyrova, Kamila AU - Stepanova, Hana AU - Rychlik, Ivan AU - Faldyna, Martin AU - Volf, Jiri PY - 2012 DA - 2012/07/20 TI - SPI-1 encoded genes of Salmonella Typhimurium influence differential polarization of porcine alveolar macrophages in vitro JO - BMC Veterinary Research SP - 115 VL - 8 IS - 1 AB - Within the last decade, macrophages have been shown to be capable of differentiating toward a classically activated phenotype (M1) with a high antimicrobial potential or an alternatively activated phenotype (M2). Some pathogens are capable of interfering with differentiation in order to down-regulate the anti-microbial activity and enhance their survival in the host. SN - 1746-6148 UR - https://doi.org/10.1186/1746-6148-8-115 DO - 10.1186/1746-6148-8-115 ID - Kyrova2012 ER -