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Table 1 Placentas from sheep and goats with naturally occurring scrapie: dam and fetal PRNP genotypes, disease status of dam

From: Sparse PrPScaccumulation in the placentas of goats with naturally acquired scrapie

Dam

   

Progeny

 

Placenta

IDa

Animal

ID

PRNP b

Parturition to

death (days)

Year born/

No. progeny

PRNP

G569

1/3684C

wt/wt

96

2006/1

wt/240P

G736A

2/3953N

240P/240P

332

2008/1

240P/240P

G736Z

2/3953N

240P/240P

332

2008/1

240P/146S240P

G742

2/3950M

wt/240P

431

2008/1

wt/240P

G797

2/3950M

wt/240P

83

2009/3

wt/240P

G836

2/3987S

240P/240P

181

2009/1

240P/240P

S345

2924

ARQ/ARQ

205

2005/3

ARQ/ARQ

S630

3345

ARQ/ARQ

249

2007/2

ARQ/ARQ

S738

3602

ARQ/ARQ

378

2008/2

ARQ/ARQ

S811

3602

ARQ/ARQ

22

2009/3

ARQ/ARQ

S758

3768

ARQ/ARQ

523

2008/1

ARQ/ARQ

S796

3768

ARQ/ARQ

181

2009/1

ARQ/ARQ

S850

4161

ARQ/ARQ

358

2009/2

ARQ/ARQ

  1. a Shed cotyledons from goats (G) or sheep (S)
  2. b PRNP genotypes included the wild type (wt) allele on a 240 S backbone with no other mutations, an allele differing only at codon 240 (240P) or an allele on the 240P backbone with a second polymorphism at codon 146 (S substituted for N) (146S240P)
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BMC Veterinary Research

ISSN: 1746-6148

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