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Table 3 Characteristics of OCT and PH permeability of barrier disrupted skin

From: The percutaneous permeation of a combination of 0.1% octenidine dihydrochloride and 2% 2-phenoxyethanol (octenisept®) through skin of different species in vitro

Parameter OCT PH
  Mean STD Mean STD
Jmax (μg/cm2/h) 9.43 9.24 2211.64 821.44
Papp (cm/s) 2.62E-06 2.57E-06 3.07E-05 1.14E-05
Recovery 6 h (%) 2.34 2.29 26.27 6.14
Recovery 28 h (%) 2.65 1.87 43.67 2.38
  1. Flux Jmax, apparent permeability coefficient Papp, and recoveries after 6 and 28 hours of PH and OCT obtained in diffusion experiments with barrier disrupted split skin of cattle after 28 hours (n = 6) calculated from the maximum absorption according to Niedorf et al. (2008) [14]