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Table 3 Characteristics of OCT and PH permeability of barrier disrupted skin

From: The percutaneous permeation of a combination of 0.1% octenidine dihydrochloride and 2% 2-phenoxyethanol (octenisept®) through skin of different species in vitro

Parameter

OCT

PH

 

Mean

STD

Mean

STD

Jmax (μg/cm2/h)

9.43

9.24

2211.64

821.44

Papp (cm/s)

2.62E-06

2.57E-06

3.07E-05

1.14E-05

Recovery 6 h (%)

2.34

2.29

26.27

6.14

Recovery 28 h (%)

2.65

1.87

43.67

2.38

  1. Flux Jmax, apparent permeability coefficient Papp, and recoveries after 6 and 28 hours of PH and OCT obtained in diffusion experiments with barrier disrupted split skin of cattle after 28 hours (n = 6) calculated from the maximum absorption according to Niedorf et al. (2008) [14]