Table 2 Echocardiographic parameters measured before (D0) and after (D6) administration of 5 mg/kg (Group 1) or 25 mg/kg (Group 2) of oral doxycycline BID during 5 consecutive days in 2 months-old healthy Belgian Blue calves.

HR (beats/min)

108 ± 13

110 ± 10

83 ± 12

95 ± 27

NS

LVIDs (cm)

3.96 ± 0.42

3.65 ± 0.51

3.29 ± 0.61

3.40 ± 0.56

NS

LVIDd (cm)

5.67 ± 0.28

5.45 ± 0.46

4.91 ± 0.62

5.09 ± 0.64

NS

IVSs (cm)

1.86 ± 0.11

1.88 ± 0.10

1.84 ± 0.17

1.83 ± 0.17

NS

IVSd (cm)

1.11 ± 0.03

1.11 ± 0.10

1.12 ± 0.18

1.16 ± 0.14

NS

FS (%)

30.19 ± 6.74

33.22 ± 4.43

33.35 ± 6.25

33.40 ± 5.48

NS

% IVS

67.05 ± 6.74

69.91 ± 8.59

65.63 ± 20.28

58.33 ± 17.06

NS

EDV (cm³)

158.40 ± 17.90

145.50 ± 19.99

115.51 ± 9.24

125.65 ± 22.68

NS

ESV (cm³)

69.13 ± 17.20

57.72 ± 14.50

45.73 ± 12.27

49.08 ± 16.16

NS

SI (ml kg^-1beat^-1)

1.17 ± 0.27

1.01 ± 0.20

0.95 ± 0.14

1.04 ± 0.16

NS

CI (ml kg^-1 min^-1)

0.13 ± 0.04

0.11 ± 0.04

0.08 ± 0.03

0.10 ± 0.03

NS

EF

0.56 ± 0.09

0.61 ± 0.05

0.61 ± 0.06

0.61 ± 0.06

NS