Table 1 Blood analysis results before (D0) and after (D6) 5 days administration of 5 mg/kg (Group 1) or 25 mg/kg (Group 2) of oral doxycycline BID in 2 months-old healthy Belgian Blue calves.
From: Clinical evaluation of cardiac effects of experimental doxycycline overdosing in healthy calves
Group 1 (n = 6) | Group 2 (n = 6) | |||||
|---|---|---|---|---|---|---|
Reference range | D0 Mean ± SD | D6 Mean ± SD | D0 Mean ± SD | D6 Mean ± SD | Group 1 vs Group 2 p | |
AST (IU/L) | 70-130 | 77 ± 13 | 77 ± 16 | 62 ± 19 | 68 ± 23 | NS |
LDH (IU/L) | 1691-2618 | 2464 ± 512 | 2578 ± 428 | 2031 ± 336 | 2169 ± 348 | NS |
CK (IU/L) | 128-244 | 270 ± 257 | 306 ± 27 | 145 ± 37 | 191 ± 79 | NS |
Iso-CK MM (%) | 55 ± 17 | 45 ± 21 | 39 ± 11 | 47 ± 16 | NS | |
Iso-CK BB (%) | 5 ± 2 | 4 ± 2 | 5 ± 2 | 3 ± 1 | NS | |
Iso-CK MB (%) | 3 ± 3 | 3 ± 2 | 3 ± 1 | 2 ± 1 | NS | |
Iso-CK MT (%) | 37 ± 14 | 49 ± 18 | 54 ± 12 | 49 ± 17 | NS | |