Table 5 Immunohistochemical score for epithelial tumor cells and fibroblasts in benign and malignant mammary tumors, expressed as the average percentage from ten fields.
From: Matrix metalloproteinases and their inhibitors in canine mammary tumors
Protein | Cell type | Immunohistochemical score (%) | p value | |
|---|---|---|---|---|
| Â | Â | Benign tumors | Malignant tumors | Â |
MMP-2 | Tumor cells | 88.6 | 67.5 | 0.05 |
| Â | Fibroblasts | 11.4 | 32.5 | Â |
MMP-9 | Tumor cells | 84.1 | 89.4 | 0.002 |
| Â | Fibroblasts | 15.9 | 10.6 | Â |
MMP-13 | Tumor cells | 56.4 | 65.9 | n.s. |
| Â | Fibroblasts | 43.6 | 34.1 | Â |
MT1-MMP | Tumor cells | 80.3 | 55.8 | 0.001 |
| Â | Fibroblasts | 19.7 | 44.2 | Â |
TIMP-2 | Tumor cells | 53.3 | 79.6 | n.s. |
| Â | Fibroblasts | 46.7 | 20.4 | Â |