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Table 5 Immunohistochemical score for epithelial tumor cells and fibroblasts in benign and malignant mammary tumors, expressed as the average percentage from ten fields.

From: Matrix metalloproteinases and their inhibitors in canine mammary tumors

Protein Cell type Immunohistochemical score (%) p value
   Benign tumors Malignant tumors  
MMP-2 Tumor cells 88.6 67.5 0.05
  Fibroblasts 11.4 32.5  
MMP-9 Tumor cells 84.1 89.4 0.002
  Fibroblasts 15.9 10.6  
MMP-13 Tumor cells 56.4 65.9 n.s.
  Fibroblasts 43.6 34.1  
MT1-MMP Tumor cells 80.3 55.8 0.001
  Fibroblasts 19.7 44.2  
TIMP-2 Tumor cells 53.3 79.6 n.s.
  Fibroblasts 46.7 20.4  
  1. n.s. = not significant