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Table 2 Blood variables from isoflurane-anesthetized horses (n = 5) breathing 50% or maximal oxygen concentrations

From: Effect of 50% and maximal inspired oxygen concentrations on respiratory variables in isoflurane-anesthetized horses

Parameter

FiO2

-5 min

15 min

30 min

60 min

90 min

120 min

150 min

180 min

+10 min

Stand + 30 min

pHa

50%

7.446 ± 0.016

7.448 ± 0.014

7.461 ± 0.011

7.429 ± 0.008

7.409 ± 0.014

7.414 ± 0.016

7.424 ± 0.012

7.412 ± 0.016

7.375 ± 0.022

7.425 ± 0.011

 

>95%

7.428 ± 0.013

7.461 ± 0.031

7.437 ± 0.032

7.424 ± 0.027

7.431 ± 0.021

7.424 ± 0.018

7.432 ± 0.014

7.441 ± 0.017

7.386 ± 0.031

7.438 ± 0.005

PaO2 (kPa)

50%

12.06 ± 0.92

12.15 ± 1.24b

12.55 ± 0.98b

13.73 ± 01.16b

13.48 ± 1.39b

12.55 ± 1.54

10.89 ± 1.43

10.29 ± 1.48

5.60 ± 0.24

12.00 ± 0.35

 

>95%

12.07 ± 0.53

36.03 ± 4.02a,b

32.13 ± 4.78a,b

36.47 ± 5.93a,b

34.18 ± 5.24a,b

31.37 ± 6.32a

29.20 ± 6.12

28.61 ± 6.34

5.92 ± 0.37

10.39 ± 1.07

Arterial Hb (g/dL)

50%

13.2 ± 1.7

12.4 ± 0.4

12.0 ± 0.5

14.1 ± 0.2

13.8 ± 0.2

13.5 ± 0.5

13.0 ± 0.7

12.8 ± 0.5

12.6 ± 0.3

11.8 ± 0.5

 

>95%

12.0 ± 0.5

11.9 ± 0.4

13.0 ± 0.6

13.7 ± 0.8

13.7 ± 0.3

13.6 ± 0.4

13.7 ± 0.7

13.3 ± 0.7

12.2 ± 0.6

11.5 ± 0.3

PaCO2 (kPa)

50%

4.84 ± 0.38

4.79 ± 0.30

4.63 ± 0.20

5.08 ± 0.08

5.53 ± 0.36

5.26 ± 0.25

5.11 ± 0.10

5.52 ± 0.32

6.76 ± 0.53a

5.59 ± 0.23

 

>95%

5.36 ± 0.23

4.57 ± 0.45

5.25 ± 0.37

5.37 ± 0.38

5.39 ± 0.31

5.51 ± 0.16

5.57 ± 0.18

5.42 ± 0.26

6.70 ± 0.76

5.76 ± 0.20

PaHCO3 (mmol/L)

50%

26 ± 1

26 ± 0

26 ± 1

26 ± 0

26 ± 1

25 ± 1

25 ± 1

26 ± 1

27 ± 1

27 ± 1

 

>95%

27 ± 1

25 ± 1

27 ± 1

26 ± 1

27 ± 0

27 ± 1

28 ± 1

28 ± 1

28 ± 0

29 ± 1

SaO2 (%)

50%

96.3 ± 0.5

95.8 ± 0.8

96.4 ± 0.4

96.4 ± 0.5

96.2 ± 0.4

95.6 ± 0.9

94.7 ± 1.3

93.4 ± 1.8

81.5 ± 1.7a

96.5 ± 0.2

 

>95%

96.8 ± 0.3

97.8 ± 0.1

97.6 ± 0.1

97.6 ± 0.2

97.6 ± 0.1

97.5 ± 0.2

97.4 ± 0.3

97.0 ± 0.7

84.0 ± 2.2a

95.1 ± 0.9

pHv

50%

7.402 ± 0.010

7.418 ± 0.011

7.433 ± 0.008

7.408 ± 0.008

7.400 ± 0.011

7.398 ± 0.011

7.397 ± 0.013

7.392 ± 0.012

7.347 ± 0.015

7.387 ± 0.008

 

>95%

7.399 ± 0.006

7.422 ± 0.027

7.408 ± 0.027

7.401 ± 0.024

7.397 ± 0.020

7.398 ± 0.016

7.402 ± 0.015

7.407 ± 0.016

7.352 ± 0.019

7.397 ± 0.004

PvO2 (kPa)

50%

4.44 ± 0.41

4.44 ± 0.09

4.61 ± 0.12

5.55 ± 0.22

5.64 ± 0.14

5.34 ± 0.27

4.95 ± 0.33

4.85 ± 0.29

3.72 ± 0.18

3.74 ± 0.21

 

>95%

4.11 ± 0.10

4.96 ± 0.11

5.08 ± 0.16

5.88 ± 0.34a

5.79 ± 0.43a

5.71 ± 0.48a

5.43 ± 0.35

5.32 ± 0.34

3.73 ± 0.19

3.59 ± 0.26

VLactate (mmol/L)

50%

0.5 ± 0

1.1 ± 0.1

1.2 ± 0.1

1.3 ± 0.1

1.4 ± 0.1a

1.4 ± 0.1a

1.5 ± 0.1a

1.5 ± 0.1a

1.4 ± 0.1a

1.1 ± 0.2

 

>95%

0.5 ± 0.1

1.2 ± 0.1

1.4 ± 0.1

1.4 ± 0.1a

1.3 ± 0.1

1.4 ± 0.1

1.5 ± 0.1a

1.5 ± 0.1a

1.4 ± 0.1a

1.2 ± 0.5

  1. Data are presented as mean ± standard error of the mean. pHa, arterial pH; PaO2, arterial partial pressure of oxygen; Arterial Hb, arterial hemoglobin; PaCO2, arterial partial pressure of carbon dioxide; PaHCO3, arterial bicarbonate; SaO2, arterial oxygen saturation; pHv, venous pH; PvO2, venous partial pressure of oxygen; vLactate, venous lactate. Time points: -5, 15, 30, 60, 90, 120, 150, and 180 represent min prior to and after induction of anesthesia; +10 min represents 10 min after disconnection from the anesthesia machine; and Stand +30 min represents 30 min after the horses stood in recovery.
  2. a Within a treatment, value is significantly different than the -5 min value for this variable.
  3. b Within this time point, value is significantly different than other treatment