Skip to main content

Table 2 Individual and mean fluke counts and clinical efficacy (%) against triclabendazole (TCBZ)-resistant Fasciola hepatica obtained after the administration of TCBZ alone (10 mg/kg, i.r.) or co-administered with ivermectin (IVM, 0.2 mg/kg, s.c.) and methimazole (MTZ, 1.5 mg/kg, i.m.) to Fasciola hepatica-infected sheep.

From: Unchanged triclabendazole kinetics after co-administration with ivermectin and methimazole: failure of its therapeutic activity against triclabendazole-resistant liver flukes

 

Untreated control

TCBZ alone

Combined treatment

 

19

2

6

 

11

12

9

 

14

8

12

 

9

5

6

Arithmetic mean

13.25

6.75

8.25

Efficacy*

-

56%

38%

  1. * The efficacy was calculated using geometric means.