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Table 2 List of the 15 biomarkers that were differentially expressed in scrapie sheep in comparison to control animals

From: Ovine serum biomarkers of early and late phase scrapie

Markers Mass (Da) Fraction Variation Healthy (n = 65) vsEP (n = 55) Healthy (n = 65) vsLP (n = 43)
     FDR (%) SAM FC AUC FDR (%) SAM FC AUC
S1 4030 F4 over 0,00 4,72 1,81 0,771 13,01 1,44 1,44 0,617
S2 4250 F1 under 0,00 -3,56 0,53 0,735 ND ND ND ND
S3 7475 F3 over 0,00 3,39 1,75 0,741 ND ND ND ND
S4 9395 F3 over 0,00 4,21 1,89 0,717 ND ND ND ND
S5 3895 F6 under ND ND ND ND 15,34 -1,99 0,38 0,702
S6 7690 F6 over ND ND ND ND 0,00 2,31 1,26 0,659
S7 9425 F6 over ND ND ND ND 0,00 3,07 1,49 0,693
S8 27450 F6 over ND ND ND ND 4,77 2,20 1,39 0,672
S9 13670 F5 over ND ND ND ND 0,00 3,15 1,39 0,683
S10 12030 F6 under ND ND ND ND 10,74 -2,91 0,79 0,625
S11 8350 F6 over ND ND ND ND 4,77 2,12 1,19 0,648
S12 7555 F1 over ND ND ND ND 0,00 2,63 1,16 0,648
S13 4575 F3 over 0,00 3,42 1,38 0,668 0,00 2,83 1,18 0,671
S14 9180 F3 over 0,00 3,98 2,00 0,707 ND ND ND ND
S15 6815 F4 under 3,34 -2,40 0,81 0,637 ND ND ND ND
  1. These peaks were selected according to their False Discovery Rate (FDR), their Fold Change (FC), their AUC ROC and the SAM test. The peak S1 and S13 were significant both in EP and LP; S2, S3, S4, S14 and S15 were significant in EP; S5, S6, S7, S8, S9, S10, S11 and S12 were significant in LP. ND: Non determined, only for non significant values.