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Figure 1 | BMC Veterinary Research

Figure 1

From: Is the presence of abnormal prion protein in the renal glomeruli of feline species presenting with FSE authentic?

Figure 1

PET-Blot analyses substantiate the specific PrPres detection in the kidney of cheetah with FSE. PET-Blot analysis allows to reveal the presence of PrPres (dark deposits) in the cerebellum (A) as well as in the adrenal gland (zona fasciculata and reticularis) (B). In the kidney from a cheetah with FSE, using immunohistochemistry, PrPsc is detected in glomerules (C), the specificity of this intense labeling can be attested by the presence of the pathological form defined by its resistance to an enzymatic digestion (PrPres) detected using the PET-Blot method (D).

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BMC Veterinary Research

ISSN: 1746-6148

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