A genomics-informed, SNP association study reveals FBLN1 and FABP4 as contributing to resistance to fleece rot in Australian Merino sheep

Table 4 SNP association results for the post-wetting trials in three populations.

SNP	Armidale			Trangie Susceptible			Trangie Resistant
	ß	R²	P	ß	R²	P	ß	R²	P
ABCIn0150	-0.10	0.23	0.696	0.01	0.02	0.882	-0.02	0.02	0.873
ABCIn0270	-0.35	3.00	0.149	0.15	1.89	0.222	0.05	0.05	0.838
ABCex0667	0.23	0.64	0.369	-0.09	0.56	0.295	0.06	0.19	0.505
FABIn20115	-0.13	0.20	0.594	n/a	n/a	n/a	n/a	n/a	n/a
FABIn20237	0.13	0.34	0.475	-0.15	1.55	0.129	0.01	0.01	0.919
FABIn30227	0.15	0.28	0.522	-0.21	0.25	0.539	0.00	0.00	0.999
FABIn30360	-0.11	0.22	0.543	0.18	1.97	0.059	-0.02	0.03	0.804
FABIn30420	0.14	0.13	0.659	-0.30	0.62	0.287	0.06	0.07	0.705
FAD1g20645	0.23	0.57	0.368	-0.18	1.17	0.187	-0.24	0.82	0.245
FBLIn100090	0.19	0.45	0.615	-0.13	1.09	0.700	-0.05	0.10	0.879
FBLIn120135	-0.19	0.60	0.403	0.00	0.00	0.965	-0.21	2.35	0.052
FBLIn120280	0.02	0.01	0.926	-0.08	0.43	0.409	0.10	0.58	0.266
FBLIn120995	0.50	4.55	0.012	0.09	0.30	0.547	0.10	0.50	0.438
FBLs10075	0.06	0.10	0.722	0.02	0.03	0.844	-0.22	3.05	0.045
HMGIn40390	0.01	0.00	0.947	-0.11	0.93	0.180	0.03	0.06	0.714
HMGIn60110	-0.22	0.62	0.401	-0.01	0.01	0.907	0.10	0.38	0.376

Statistics are as follows: ß: Regression coefficient of fleece rot score on genotype (indicating the average change in fleece rot score for each copy of an allele); R²: Percentage of phenotypic variation explained by the SNP (%); P-value: Probability value associated with the test ß = 0. Statistics corresponding to significant associations are highlighted in bold type.

ISSN: 1746-6148