Table 2 Results of rapid test (ELISA TeSeE), immunoblot (TeSeE Western Blot), IHC (cocktail of 2G11 and F89/160.1.5) and PrP genotypes of AS cases.
From: Atypical/Nor98 scrapie in the Basque Country: a case report of eight outbreaks
2004 | 2005 | 2008 | 2009 | |||||
|---|---|---|---|---|---|---|---|---|
M7 | M72 | M45 | M31 | M15 | M19-1 | M27 | M9-2 | |
Origin | Fallen stock | Fallen stock | Slaughtered | Slaughtered | Fallen stock (Advanced autolysis) | Fallen stock | Slaughtered | Slaughtered |
Month of death | June | November | April | January | February | December | February | April |
Province | Vizcaya | Alava | Guipuzcoa | Guipuzcoa | Alava | Guipuzcoa | Guipuzcoa | Guipuzcoa |
Age (years) | 6.3 | 12.8 | 4.3 | 7.0 | 9.1 | 5.6 | 8.1 | 10.3 |
Genotype | AFRQ ALRQ | ALRR ALRQ | AFRQ ALRQ | AFRQ AFRQ | AFRQ AFRQ | AFRQ ALHQ | ALRQ ALRH | ALRQ ALRQ |
Clinical symptoms | Not registered | Not registered | Not registered | Yes | Not registered | Not registered | Not registered | Not registered |
Rapid test result (cut off) | 0.377 (0.218) | 0.387 (0.219) | 1.112 (0.219) | 2.788 (0.230) | 2.859 (0.230) | 2.710 (0.219) | 0.498 (0.102) | 1.289 (0.103) |
WB TeSeE | ||||||||
Obex-Cerebellum | 1 | 2 | 3 | 2 | 3 | 1 | 1 | 2 |
Cerebellum | 0 | 0 | 3 | 3 | 1 | 3 | 1 | 3 |
Cerebral Cortex | 0 | 0 | 1 | 0 | 2 | 1 | 1(3)* | 2 |
IHC | ||||||||
MO | PC | NA | NA | 2 | 1 | 1 | 1 | 1 |
Cerebellum | 1 | 3 | 3 | 3 | 1 | 3 | 1 | 3 |
Frontal Lobe | PC | NA | 2 | NA | 3 | 1 | 2 | 1 |