Table 1 mRNA and protein expression levels of HEPACAM1 and 2 in tissue samples of non-neoplastic canine mammary gland and canine mammary tumours
Gene | Normal gland | Adenoma | Carcinoma | IVTC | Lymph node metastases |
|---|---|---|---|---|---|
Average fold change in mRNA expression levels relative to normal gland of the same dog | |||||
HEPACAM1* | 1 | 5.2 (SD ± 2.4) | 1.9 (SD ± 1.2) | - | 1.5 (SD ± 1.2) |
HEPACAM2* | 1 | 4.0 (SD ± 2.0) | 0.1 (SD ± 0.4) | - | 0.1 (SD ± 0.3) |
Percentage of immunohistochemical HEPACAM positive tissue samples | |||||
HEPACAM1 | 100% | 13% | 94% | 95% | 89% |